There is a vast amount of research
on the effects of the treatment of ADD/ADHD children with
psychostimulants beginning with the following:
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There is a vast amount of research on the effects of the treatment of
ADD/ADHD children with psychostimulants beginning with the following:
Bradley, W. (1937). The behavior of children receiving benzedrine. American
Journal of Psychiatry, 94, 577-585.
Bradley, W., & Bowen, C. (1940). School performance of children receiving
amphetamine (benzedrine) sulfate. American Journal of Orthopsychiatry.
The following lists published research conducted by a few of the leading
national experts. It represents a very small sample of the research that's
been conducted relative to the treatment of ADHD children with
psychostimulants. By the way, it's only in recent years that stimulant
treatment has been prescribed for adults with ADHD since the thinking used to
be that kids would outgrow it in adolescence. Therefore, while there's a
tremendous amount of research on the effects of stimulant treatment on
ADD/ADHD children, there's very little on the treatment of ADHD adults with
stimulants. Here's a very small sample:
Biederman, J., Baldessarini, R.J., Wright, V., Knee, D., & Harmatz, J.S.
(1989). A double-blind placebo controlled study of desipramine in the
treatment of ADD: I. Efficacy. Journal of the American Academy of Child and
Adolescent Psychiatry, 28, 777-784.
Biederman, J., Baldessarini, R.J., Wright, V., Knee, D., & Harmatz, J.S. &
Goldblatt, A. (1989). A double-blind placebo controlled study of desipramine
in the treatment of ADD: II. Serum drug levels and cardiovascular findings.
Journal of the American Academy of Child and Adolescent Psychiatry, 28,
Barkley, R.A. (1976). Predicting the response of hyperactive children to
stimulant drugs: A review. Journal of Abnormal Psychology, 4, 327-348.
Barkley, R.A. (1977a). The effects of methylphenidate on various measures of
activity level and attention in hyperkinetic children. Journal of Abnormal
Child Psychology, 5, 351-369.
Barkley, R.A. (1977b). A review of stimulant drug research with hyperactive
children. Journal of Child Psychology and Psychiatry, 18, 137-165.
Barkley, R.A. (1988e). The effects of methylphenidate on the interactions of
preschool ADHD children with their mothers. Journal of the American Academy
of Child and Adolescent Psychiatry, 27, 336-341.
Barkley, R.A. (1989b). Hyperactive girls and boys: Stimulant drug effects on
mother-child interactions. Journal of Child Psychology and Psychiatry, 30,
Barkely, R.A. & Cunningham, C.E. (1978) Do stimulant drugs improve the
academic performance of hyperkinetic children? A review of outcome research.
Clinical Pediatrics, 17, 85-92.
Barkley, R.A., Karlsson, J., Strzelecki, E., & Murphy, J. (1984). Effects of
age and ritalin dosage on mohter-child interactions of hyperactive children.
Journal of Consulting & Clinical Psychology, 52, 750-758.
Barkley, R.A., McMurray, M.B., Edelbrock, C.S., & Robbins, K. (1989). The
response of aggressive and non-aggressive ADHD children to two doses of
methylphenidate. Journal of the American Academy of Child and Adolescent
Psychiatry, 28, 873-881.
Conners, C.K. (1966). The effects of dexedrine on rapid discrimination and
motor control of hyperkinetic children under mild stress. Journal of Nervous
and Mental Disease, 142, 420-433.
Conners, C.K., & Taylor, E. (1980). Pemoline, methylphenidate, and placebo in
children with minimal brain dysfunction. Archives of General Psychiatry, 37,
Rapoport, J.L., Buchsbaum, M.S., Zahn, T.P., Weingartner, H., Ludlow, C., &
Mikkelsen, E.J. (1978). Dextroamphetamine: Cognitive and behavioral effects
in Normal prepubertal boys. Science, 199, 560-563.
Finally, as to why the FDA isn't up to speed on the reseach done on the
effects of psychostimulant treatment for ADD/ADHD children, I'd say it shows
gross incompetance in that agency.
Also, keep in mind that there's lots of research going on in the field of
medicine which is disconnected from the government, and isn't dependent on
government grants and funding.
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