
<a href="../99/07/addstudy.txt"> There is a vast amount of research
on the effects of the treatment of ADD/ADHD children with
psychostimulants beginning with the following:</a>



\doc\web\99\07\addstudy.txt
From:           	Nanny714@aol.com
Date sent:      	Sat, 1 May 1999 14:44:47 EDT
Subject:        	[education-consumers] Re:Request for Test information on Ritalin 
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Marlene,
    There is a vast amount of research on the effects of the treatment of 
ADD/ADHD children with psychostimulants beginning with the following:

Bradley, W. (1937). The behavior of children receiving benzedrine. American 
Journal of Psychiatry, 94, 577-585.
Bradley, W., & Bowen, C. (1940). School performance of children receiving 
amphetamine (benzedrine) sulfate. American Journal of Orthopsychiatry.

The following lists published research conducted by a few of the leading 
national experts. It represents a very small sample of the research that's 
been conducted relative to the treatment of ADHD children with 
psychostimulants. By the way, it's only in recent years that stimulant 
treatment has been prescribed for adults with ADHD since the thinking used to 
be that kids would outgrow it in adolescence. Therefore, while there's a 
tremendous amount of research on the effects of stimulant treatment on 
ADD/ADHD children, there's very little on the treatment of ADHD adults with 
stimulants. Here's a very small sample:

Biederman, J., Baldessarini, R.J., Wright, V., Knee, D., & Harmatz, J.S. 
(1989). A double-blind placebo controlled study of desipramine in the 
treatment of ADD:  I. Efficacy. Journal of the American Academy of Child and 
Adolescent Psychiatry, 28, 777-784.
Biederman, J., Baldessarini, R.J., Wright, V., Knee, D., & Harmatz, J.S. & 
Goldblatt, A. (1989). A double-blind placebo controlled study of desipramine 
in the treatment of ADD:  II. Serum drug levels and cardiovascular findings. 
Journal of the American Academy of Child and Adolescent Psychiatry, 28, 
903-911.

Barkley, R.A. (1976). Predicting the response of hyperactive children to 
stimulant drugs:  A review. Journal of Abnormal Psychology, 4, 327-348.
Barkley, R.A. (1977a). The effects of methylphenidate on various measures of 
activity level and attention in hyperkinetic children. Journal of Abnormal 
Child Psychology, 5, 351-369.
Barkley, R.A. (1977b). A review of stimulant drug research with hyperactive 
children. Journal of Child Psychology and Psychiatry, 18, 137-165.
Barkley, R.A. (1988e). The effects of methylphenidate on the interactions of 
preschool ADHD children with their mothers. Journal of the American Academy 
of Child and Adolescent Psychiatry, 27, 336-341.
Barkley, R.A. (1989b). Hyperactive girls and boys:  Stimulant drug effects on 
mother-child interactions. Journal of Child Psychology and Psychiatry, 30, 
379-390.
Barkely, R.A. & Cunningham, C.E. (1978) Do stimulant drugs improve the 
academic performance of hyperkinetic children? A review of outcome research. 
Clinical Pediatrics, 17, 85-92.
Barkley, R.A., Karlsson, J., Strzelecki, E., & Murphy, J. (1984). Effects of 
age and ritalin dosage on mohter-child interactions of hyperactive children. 
Journal of Consulting & Clinical Psychology, 52, 750-758.
Barkley, R.A., McMurray, M.B., Edelbrock, C.S., & Robbins, K. (1989). The 
response of aggressive and non-aggressive ADHD children to two doses of 
methylphenidate. Journal of the American Academy of Child and Adolescent 
Psychiatry, 28, 873-881.

Conners, C.K. (1966). The effects of dexedrine on rapid discrimination and 
motor control of hyperkinetic children under mild stress. Journal of Nervous 
and Mental Disease, 142, 420-433.
Conners, C.K., & Taylor, E. (1980). Pemoline, methylphenidate, and placebo in 
children with minimal brain dysfunction. Archives of General Psychiatry, 37, 
922-932.

Rapoport, J.L., Buchsbaum, M.S., Zahn, T.P., Weingartner, H., Ludlow, C., & 
Mikkelsen, E.J. (1978). Dextroamphetamine: Cognitive and behavioral effects 
in Normal prepubertal boys. Science, 199, 560-563.
______________________________________________________________________
Finally, as to why the FDA isn't up to speed on the reseach done on the 
effects of psychostimulant treatment for ADD/ADHD children, I'd say it shows 
gross incompetance in that agency.
Also, keep in mind that there's lots of research going on in the field of 
medicine which is disconnected from the government, and isn't dependent on 
government grants and funding.

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